The most recommended material for laser engraving and cutting is vegetable-tanned leather (veg-tan). This natural hide is safe to laser because it doesn't contain toxic chemicals and produces clean, dark results when engraved. While genuine leather (like cowhide) is suitable, you must strictly avoid chrome-tanned leather. When heated, chrome-tanned leather releases toxic chromium gases that are hazardous and can severely damage your laser engraver for leather.