Choose multi processing and then choose cardstock as your material since cutting the cardstock will process first

Select black layers and choose no out put and then set your cut settings (100 power, 3 speed, 1 pass).

Keep the default cut settings for the blue layer and process it to start cutting it (make sure to install the fine point blade, blue sticky mat, and cardstock before framing and cutting)

Once the blue layer has been cut, remove the fine point blade and install the laser module. 

Select the blue layer and change to no output. Select black layers and switch to yet output.

Frame and then process.

Once all layers have been cut, assemble accordingly by using glue and paint.